Cutaneous tuberculosis and phlyctenular keratoconjunctivitis: a forgotten association.
نویسندگان
چکیده
Cutaneous tuberculosis may be associated with concurrent systemic foci in the body such as lung, lymph node, bone or CNS. Phlyctenular keratoconjunctivitis (PKC) is a manifestation of immunological response to a variety of antigens in the eye, tubercular focus (evident or occult) being the commonest in India. Reports in the existing literature have shown lungs and lymph nodes to be the predominant underlying focus associated with PKC, whereas cutaneous tuberculosis has seldom been found in this situation. We report this forgotten association in two children with cutaneous tuberculosis, one each with lupus vulgaris and scrofuloderma, who also had PKC. Interestingly, one of the cases also had simultaneous lichen scrofulosorum, which is also an immunological response to tubercular antigen and manifests in the skin, thus showing immunological manifestation in two different organ systems along with cutaneous focus of tuberculosis.
منابع مشابه
Phlyctenular eye disease: a reappraisal.
PURPOSE Phlyctenular keratoconjunctivitis is a nonspecific allergic response in the cornea and/or conjunctiva to a variety of distinct conditions. Tuberculosis as an etiological association is being supplanted by staphylococcal infection and worm infestation in developed countries. Our aim was to determine the relative frequency of the various known etiological factors of phlyctenular keratocon...
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Phlyctenular keratoconfunctivitis is a clinical entity but not an etiological entity. There is general agreement that it is a manifestation of bacterial allergy, most often to products of the tubercle bacillus. The reason for the focal nature of the disease, the mechanism by which attacks are precipitated, and the all but specific role of Mycobacterium tuberculosis remain to be elucidated. Alth...
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PURPOSE To report an atypically severe and refractory phlyctenular keratoconjunctivitis case treated successfully with systemic biologic immunosuppressive therapy. METHODS A 10-year-old female was followed in the ophthalmology clinic for three years for a severe form of bilateral PKC. The patient was treated for blepharitis and intestinal parasitosis, and underwent topical corticosteroid ther...
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ورودعنوان ژورنال:
- Indian journal of dermatology, venereology and leprology
دوره 72 4 شماره
صفحات -
تاریخ انتشار 2006